T Cell Immunity Testing
Examining T Cell Immune Response for Critical Decisions
Innovations in Immunity
inSIGHT™ T Cell diagnostic delivers a deeper understanding of patients' response to viral antigens
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Assess current immune response for viral target
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Confirm if virus specific CD4 and CD8 T Cells are present
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Evaluate treatment decisions
Learn more about Eurofins Viracor inSIGHT™ for examining T cell response:
EBV inSIGHT™ T Cell Immunity test is now available to order.
The test measures the strength of T cell responses to EBV specific antigens, lytic antigen BZLF1 and latent antigen EBNA3. It evaluates and reports polyfunctional and Interferon-gamma activity of CD4 and CD8 T cell responses independently.
In the transplant setting, post-transplant lymphoproliferative disorders (PTLD) can arise as a consequence of immunosuppression and the loss of T cells that typically control reactivation of EBV. Rapidly rising EBV viral loads can indicate patients at risk for PTLD, a critical cause of morbidity and mortality in, SOT and HSCT patients
It's your job to keep patients safe; our job is to help you do it.
The Advantages of inSIGHT™
With inSIGHT™, you're now armed with the data to help answer critical questions: Is the patient's body producing a T Cell response? Is that response strong enough to make treatment adjustments? Are they ready to discontinue antiviral medication?
For Clinical Staff
- Reports CD4 and CD8 responses separately
- Provides numerical values for various reportables
- Ability for result consultation with scientific liaisons
For Lab Staff
- Does not require additional staff or training
- Live cell ambient shippers available
- Simple blood draw, no extra processing to isolate PBMC
CASE STUDY: Review a bi-lateral lung transplant patient case study to see how they utilized inSIGHT testing to evaluate prophylaxis.
CMV Immunity Testing in a Lung Transplant Recipient
The ability to monitor the presence or absence of virus specific, highly functional T cells will be an important tool, along with monitoring viral load, in managing patients post-transplant as their immune system recovers."
~ Eurofins Viracor
ABSTRACT POSTER PRESENTATION
Detection of Epstein-Barr Virus Specific Functional T Cells By Flow Cytometry
The ability to evaluate EBV specific T cell responses post-transplant is currently an unmet need for managing patients at risk of developing post-transplant lymphoproliferative disorder (PTLD). Functional impairment or lack of a T cell response to EBV has been predicted to drive the development of PTLD. Research indicates...
View the full poster presentation
Flebbe-Rehwaldt, L. Detection of Epstein-Barr Virus Specific Functional T Cells by Flow Cytometry. In: The 2022 Tandem Meetings | Transplantation & Cellular Therapy Meetings of ASBMT and CIBMTR; April 23-26; Salt Lake City, UT; Abstract Number 479.
Results Reporting
WHITE PAPER
Evaluating Cytomegalovirus Cell Mediated Immunity Diagnostic Assays
T Cell Immunity Testing - Flow Cytometry
How It Works
inSIGHT™ utilizes intracellular cytokine staining analyzed by flow cytometry to measure the strength of T cell responses to viral specific antigens or proteins. It evaluates and reports the activity of CD4 and CD8 T Cell responses separately.
